JOURNAL OF SURGICAL RESEARCH, vol.87, no.2, pp.232-238, 1999 (SCI-Expanded)
Article / Article
JOURNAL OF SURGICAL RESEARCH
Science Citation Index Expanded (SCI-EXPANDED), Scopus
cell adhesion molecule, ischemia, reperfusion, hemorrhagic shock, leukocyte, dextran, pentoxifylline, ENDOTHELIAL CELL-INTERACTIONS, MICROVASCULAR BLOOD-FLOW, REPERFUSION INJURY, HYPERTONIC SALINE, CRYSTALLOID RESUSCITATION, MOLECULAR MECHANISMS, FLUID RESUSCITATION, TISSUE-INJURY, IN-VIVO, RATS
Dokuz Eylül University Affiliated:
Background. Dextran and pentoxifylline have been shown to prevent leukocyte-endothelium adherence encountered after hemorrhagic shock, P-Selectin is the first endothelial cell adhesion molecule to be upregulated after an ischemic insult. We investigated the effects of resuscitation with dextran 70 and administration of pentoifylline during resuscitation on hemorrhagic shock-induced P-selectin expression.