Impaired coronary blood flow may be related to elevated homocysteine levels in patients with metabolic syndrome

Alihanoglu Y. I., Yildiz B. S., ÖZCAN E. E., Kilic D. I., Kuru D. S., Taskoylu O., ...More

WIENER KLINISCHE WOCHENSCHRIFT, vol.127, no.21-22, pp.864-870, 2015 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 127 Issue: 21-22
  • Publication Date: 2015
  • Doi Number: 10.1007/s00508-015-0854-z
  • Journal Name: WIENER KLINISCHE WOCHENSCHRIFT
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.864-870
  • Keywords: Metabolic syndrome, Homocysteine, Coronary flow rate, TIMI frame count
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background Metabolic syndrome (MS) refers to a group of cardiovascular risk factors associated with endothelial dysfunction and impaired coronary blood flow (CBF). Homocysteine (Hcy) is another risk factor for the development of insulin resistance and endothelial dysfunction. However, the relationship between Hcy levels and CBF in patients with MS has not been investigated specifically. In the present study, we aimed to evaluate the relationship between Hcy levels and CBF in MS patients with normal coronary arteries.