Discrimination Effectiveness of CK18 on Cell Death Modes in Colon Cancer Cells
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.35, sa.1, ss.20-28, 2010 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 35 Sayı: 1
- Basım Tarihi: 2010
- Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.20-28
- Anahtar Kelimeler: CK18, cell death, apoptosis, colon cancer, FOLFIRI
- Dokuz Eylül Üniversitesi Adresli: Evet
Özet
Objectives: Cytokeratin-18 is an intermediate filament that could be a candidate cell death marker in monitoring chemotherapy efficiency. The aim of this study was to evaluate cell death determination effectiveness of CK18 ELISA assay in HCT-116 colon cancer cells treated with clinical compatible dosages of FOLFIRI chemotherapy combination.