TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.35, no.1, pp.20-28, 2010 (SCI-Expanded)
Objectives: Cytokeratin-18 is an intermediate filament that could be a candidate cell death marker in monitoring chemotherapy efficiency. The aim of this study was to evaluate cell death determination effectiveness of CK18 ELISA assay in HCT-116 colon cancer cells treated with clinical compatible dosages of FOLFIRI chemotherapy combination.