Comparison of Clinical Characteristics and Prognostic Laboratory Findings of COVID-19 Patients by Age Groups


EREN KUTSOYLU O. Ö., NAZLI ZEKA A., ÖMEROĞLU ŞİMŞEK G., APPAK Ö., BAYRAM B., ÖZGEN ALPAYDIN A., ...Daha Fazla

INFECTIOUS DISEASES AND CLINICAL MICROBIOLOGY, cilt.3, sa.3, ss.120-128, 2021 (ESCI, TRDizin) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 3 Sayı: 3
  • Basım Tarihi: 2021
  • Doi Numarası: 10.36519/idcm.2021.76
  • Dergi Adı: INFECTIOUS DISEASES AND CLINICAL MICROBIOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.120-128
  • Anahtar Kelimeler: COVID-19, SARS-CoV-2, age groups, clinical features, prognosis
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: In this study, we determined the symptoms of the COVID-19 and defined age -specific symptoms that can help diagnose the disease on hospital admission. Materials and Methods: Patients who visited a university hospital's adult pandemia outpatient clinic with suspected COVID-19 symptoms and tested with SARS-CoV-2 polymerase chain reaction test between March 17 - May 17, 2020, were included in the study. Demographic data, symptoms on admission, prognostic laboratory tests and hospitalization were recorded. Results: Out of 5289 admissions, 639 (12.1%) patients had suspected or confirmed COVID-19. Patients were sorted incident to age groups to determine the difference in demographic data, comorbidities, symptoms, prognostic laboratory findings and outcome. The exposure history was lower in the 65-79 age group, contrary to the >= 80 age group. Sore throat, loss of smell and taste, headache and myalgia were specific to the 18-49 age group (p<0.001). Shortness of breath was represented 2.31 and 2.79 times higher in the 65-79 and the >= 80 age group, respectively, than the 18-49 age group. Comorbid diseases, prognostic laboratory tests (lymphopenia, C-reactive protein (CRP), D-dimer, ferritin) and hospitalization were found significantly higher in the >= 65 age group than the 18-49 age group. Conclusion: This study identifies the varieties in comorbidities, symptoms, prognostic laboratory findings and outcomes between the age-grouped patients referred to the outpatient clinic with suspected or confirmed COVID-19. We found that comorbidities, poor prognostic factors and hospitalization are more common in patients over 65 years. Shortness of breath is the most common symptom seen in the >= 65 age group compared to the 18-49 age group, where sore throat, loss of taste and smell are the symptoms commonly seen. Predominant symptoms for age groups help physicians differentiate the disease in clinical practice.