Taurine suppresses oxidative stress-potentiated expression of lectin-like oxidized low-density lipoprotein receptor and restenosis in balloon-injured rabbit iliac artery

Gokce G., Ozsarlak-Sozer G., Oran I., Oktay G., Ozkal S., Kerry Z.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, cilt.38, sa.12, ss.811-818, 2011 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 12
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1111/j.1440-1681.2011.05612.x
  • Dergi Adı: CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.811-818
  • Anahtar Kelimeler: balloon injury, glutathione, lectin-like oxidized low-density lipoprotein receptor (LOX-1), restenosis, taurine
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

1. In endothelial cells, the major receptor for the binding and internalization of oxidized low-density lipoprotein (LDL) is the lectin-like oxidized LDL receptor (LOX-1). The aim of the present study was to investigate the effects of taurine on intimal thickening and LOX-1 expression under normal and oxidative conditions.