Taurine suppresses oxidative stress-potentiated expression of lectin-like oxidized low-density lipoprotein receptor and restenosis in balloon-injured rabbit iliac artery
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, vol.38, no.12, pp.811-818, 2011 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 38 Issue: 12
- Publication Date: 2011
- Doi Number: 10.1111/j.1440-1681.2011.05612.x
- Journal Name: CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.811-818
- Keywords: balloon injury, glutathione, lectin-like oxidized low-density lipoprotein receptor (LOX-1), restenosis, taurine
- Dokuz Eylül University Affiliated: Yes
Abstract
1. In endothelial cells, the major receptor for the binding and internalization of oxidized low-density lipoprotein (LDL) is the lectin-like oxidized LDL receptor (LOX-1). The aim of the present study was to investigate the effects of taurine on intimal thickening and LOX-1 expression under normal and oxidative conditions.