A Preliminary Observation of Increased Glial Cell Line-Derived Neurotrophic Factor in Manic Switch due to Electroconvulsive Treatment in Depressive Patients

Tunca Z., Bayin M., ALKIN T., Ozerdem A., Resmi H., AKAN P.

JOURNAL OF ECT, cilt.31, sa.3, ss.167-172, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 3
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1097/yct.0000000000000198
  • Dergi Adı: JOURNAL OF ECT
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Sayfa Sayıları: ss.167-172
  • Anahtar Kelimeler: BDNF, brain-derived neurotrophic factor, GDNF, glial cell line-derived neurotrophic factor, depression, electroconvulsive treatment (ECT), manic switch, depressive relapse
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective Neurotrophic factors are known to be involved in the pathogenesis of mood disorders. However, the precise neurobiology underlying relapse into depression or switch to mania under antidepressant treatment is not fully understood. Evidence suggests the role of neuroplasticity in these processes.