Effect of doxazosin with and without rho-kinase inhibitor on human corpus cavernosum smooth muscle in the presence of bladder outlet obstruction

Demir O., Murat N., Aslan G., Gidener S., Esen A. A.

JOURNAL OF UROLOGY, cilt.175, sa.6, ss.2345-2349, 2006 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 175 Sayı: 6
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/s0022-5347(06)00281-3
  • Dergi Adı: JOURNAL OF UROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2345-2349
  • Anahtar Kelimeler: penis, impotence, prostatic hyperplasia, doxazosin, Y 27632, BENIGN PROSTATIC HYPERPLASIA, TRACT SYMPTOMS LUTS, NITRIC-OXIDE, DYSFUNCTION, CONTRACTILITY, RELAXATION, RABBITS, Y-27632, TONE
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Purpose: We investigated the relationship of adrenergic responses in corpus cavernosum tissues in the presence of BOO using the alpha 1-adrenergic receptor antagonist doxazosin (Pfizer, New York, New York) and the rho-kinase inhibitor Y-27632 (Calbiochem, San Diego, California).