Chaperonin (HSP60) and annexin-2 are candidate biomarkers for non-small cell lung carcinoma
MEDICINE, cilt.96, sa.6, 2017 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 96 Sayı: 6
- Basım Tarihi: 2017
- Doi Numarası: 10.1097/md.0000000000005903
- Dergi Adı: MEDICINE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Anahtar Kelimeler: annexin-2, cancer screening, chaperonin, lung cancer, protemic
- Dokuz Eylül Üniversitesi Adresli: Evet
Özet
Background: Lung cancer is responsible of 12.4% and 17.6% of all newly diagnosed cancer cases and mortality due to cancer, respectively, and 5-year survival rate despite all improved treatment options is 15%. This survival rate reaches 66% in the Stage 1 and surgically treated patients. Early diagnosis which could not be definitely and commonly achieved yet is extremely critical in obtaining high survival rate in this disease. For this reason; proteomic differences were evaluated using matrix assisted laser desorption ionization (MALDI) mass spectrometry in the subgroups of lung adenocarcinoma and squamous cell carcinoma.