The effects of intraamniotic human neonatal urine and meconium on the intestines of the chick embryo with gastroschisis

OLGUNER M., Akgur F., Api A., Ozer E., Aktug T.

JOURNAL OF PEDIATRIC SURGERY, vol.35, no.3, pp.458-461, 2000 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 3
  • Publication Date: 2000
  • Doi Number: 10.1016/s0022-3468(00)90214-8
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.458-461
  • Keywords: gastroschisis, intestinal damage, fetal defecation, intraamniotic meconium, ALLANTOIC FLUID EXCHANGE, AMNIOTIC-FLUID, DAMAGE, ETIOLOGY, BOWEL, DEFECATION, PREVENTION, FETUS, MODEL
  • Dokuz Eylül University Affiliated: No


Background/Purpose: Urinary waste products in the amniotic fluid has been implicated as a cause of intestinal damage (ID) in gastroschisis based on the fact that fetus urinates physiologically into the amniotic cavity. However, experimental and clinical data suggest that intrauterine defecation is a physiological event, thus gastrointestinal waste products also may be responsible for ID in gastroschisis. An experimental study was performed to investigate the effects of intraamniotic human neonatal urine and diluted meconium on the intestines of chick embryo with gastroschisis.