Hemangiomas of Childhood: Analysis of 116 Cases

Gunes D., Cecen E., Ozguven A. A., Kocaoglu S., Kenan Y., Gul S., ...Daha Fazla

TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, cilt.29, sa.5, ss.1137-1148, 2009 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 5
  • Basım Tarihi: 2009
  • Dergi Adı: TURKIYE KLINIKLERI TIP BILIMLERI DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1137-1148
  • Anahtar Kelimeler: Hemangioma, complications, treatment, childhood, infantile, VASCULAR MALFORMATIONS, INFANTILE HEMANGIOMAS, INFANCY, CLASSIFICATION, TUMORS, CREAM
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: Hemangiomas are the most common benign vascular tumors of infancy. The purpose of this study was to evaluate children with hemangiomas who were followed up at our center between 2000 and 2007. Material and Methods: Medical records of children with hemangiomas were analyzed retrospectively for patient characteristics, features of hemangiomas, complications and treatments. Results: In 116 children with hemangiomas, the median age was 6 months (0-14 years), M:F ratio was 0.63. There were 113 patients with skin hemangiomas and of them 61% had solitary lesion. Head-neck hemangiomas were observed in 53% of patients. Hemangiomas were capillary (26%), cavernous (49%), or mixed (25%). The majority of patients (74%) had presented in the proliferative phase while the remaining were in the involution phase. After the initial evaluation, 42% of patients were lost to follow-up. Complications, including ulceration / bleeding (19%), infections (12%), visual (12%) and hearing (3%) compromise occurred in 34% of the 67 patients who attended the follow-up visits. Systemic corticosteroid was given in 10 patients with hemangiomas threatening vision or hearing and in 5 patients for recurrent local complications. Intralesional corticosteroid (n=4) and interferon-alpha (n=1) were administered in 5 cases in addition to corticosteroid. Surgery was performed in 3 patients. Conclusion: Infantile hemangiomas were commonly located at the head-neck region, and patients were usually admitted in the proliferative phase. The majority of patients with no indication for treatment were lost to follow-up. Treatment was necessary only in complicated hemangiomas. Corticosteroids remain the mainstay of treatment for those hemangiomas.