Data and programs in support of network analysis of genes and their association with diseases

Kontou P. I., Pavlopoulou A., Dimou N. L., Pavlopoulos G. A., Bagos P. G.

DATA IN BRIEF, cilt.8, ss.1036-1039, 2016 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.dib.2016.07.022
  • Dergi Adı: DATA IN BRIEF
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.1036-1039
  • Anahtar Kelimeler: Gene-disease associations, Gene-gene networks, Disease-disease networks, CATALOG
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

The network-based approaches that were employed in order to depict the relationships between human genetic diseases and their associated genes are described. Towards this direction, mono partite disease-disease and gene-gene networks were constructed from bipartite gene-disease association networks. The latter were created by collecting and integrating data from three diverse resources, each one with different content, covering from rare monogenic disorders to common complex diseases. Moreover, topological and clustering graph analyses were performed. The methodology and the programs presented in this article are related to the research article entitled "Network analysis of genes and their association with diseases" [1]. (C) 2016 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license.