Evaluation of Immunhistochemical ERG Tissue Expression in Wilms Tumor

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Diniz G., Birol I. E., Oniz H., Vergin C., Aktas S.

IZMIR DR BEHCET UZ COCUK HASTANESI DERGISI, cilt.10, sa.1, ss.65-70, 2020 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Sayı: 1
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5222/buchd.2020.94759
  • Dergi Adı: IZMIR DR BEHCET UZ COCUK HASTANESI DERGISI
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.65-70
  • Anahtar Kelimeler: Wilms tumor, nephroblastoma, ERG, ETS, transcription factor, ETS TRANSCRIPTION FACTORS, ANDROGEN RECEPTOR, PROSTATE, FUSIONS
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: The ETS-related gene (ERG) is an oncogene that encodes one of the erythroblast transformation specific (ETS) transcription factors. Although there are many studies on their effects on the development of different malignancies, mainly prostate cancer, Ewing sarcoma and acute myeloid leukemia, its association with Wilms tumor has never been investigated. The aim of this study was to evaluate ERG tissue expression in Wilms tumors.