Efficacy of Topical Brinzolamide Treatment in Posterior Microphthalmos-Related Macular Cystoid Lesions: A Case Series

Engin C. D., Ekinci U. B., Selver A., SAATCİ A. O.

TURK OFTALMOLOJI DERGISI-TURKISH JOURNAL OF OPHTHALMOLOGY, cilt.50, sa.1, ss.44-49, 2020 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 50 Sayı: 1
  • Basım Tarihi: 2020
  • Doi Numarası: 10.4274/tjo.galenos.2019.40504
  • Dergi Adı: TURK OFTALMOLOJI DERGISI-TURKISH JOURNAL OF OPHTHALMOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.44-49
  • Anahtar Kelimeler: Brinzolamide, macular cystoid lesion, retinoschisis, posterior microphthalmos, PAPILLOMACULAR FOLD, CARBONIC-ANHYDRASE, DORZOLAMIDE, RETINOSCHISIS, MANAGEMENT, FEATURES, EDEMA
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

The aim of this study was to report the outcome of topical brinzolamide 1% treatment on macular cystoid lesions resembling retinoschisis in 4 patients diagnosed with posterior microphthalmia. The medical records of 4 patients with a clinical diagnosis of posterior microphthalmia who had started topical brinzolamide 1% treatment were reviewed. Visual acuity, central foveal thickness, and cystoid lesion area percentage were used to evaluate treatment response. In the follow-up, there was a decrease in central foveal thicknesses and cystoid lesion area percentages in both eyes of 3 of the patients. However, 1 patient showed increases in both parameters. Visual acuity remained stable in 5 eyes and increased in 3 eyes. Topical brinzolamide treatment may have some positive effects on macular cystoid lesions in selected cases.