Altered expression of interstitial cells of Cajal in primary obstructive megaureter

Kart Y., Karakus O. Z., ATEŞ O., HAKGÜDER F. G., OLGUNER M., Akgur F. M.

JOURNAL OF PEDIATRIC UROLOGY, vol.9, no.6, pp.1028-1031, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 9 Issue: 6
  • Publication Date: 2013
  • Doi Number: 10.1016/j.jpurol.2013.02.003
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1028-1031
  • Keywords: Interstitial cells of Cajal, Ureterovesical junction obstruction, Megaureter, UPPER URINARY-TRACT, JUNCTION OBSTRUCTION, HIRSCHSPRUNG-DISEASE, DILATED URETER, CHILDHOOD
  • Dokuz Eylül University Affiliated: Yes


Objective: A marked decrease in the density of interstitial cells of Cajal (ICC) has been shown in patients with ureteropelvic junction obstruction. ICC may also play a role in primary obstructive megaureter (POM). An immunohistochemical study was conducted to investigate the density of ICC in ureterovesical junction (UVJ) segments resected from patients with POM and from control autopsy specimens.