The Protective Effects of Acetyl L-Carnitine on Testis Gonadotoxicity Induced by Cisplatin in Rats

Coskun N., Hatipoglu M. T., ÖZOĞUL C., Korkmaz C., Akyol S. N., CİLAKER MIÇILI S., ...More

BALKAN MEDICAL JOURNAL, vol.30, no.2, pp.235-241, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 2
  • Publication Date: 2013
  • Doi Number: 10.5152/balkanmedj.2013.7340
  • Journal Name: BALKAN MEDICAL JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.235-241
  • Keywords: Acetyl L-carnitine, cisplatin, gonadotoxicity, testis, OXIDATIVE STRESS, TOXICITY, NEUROTOXICITY, OTOTOXICITY, CANCER
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background: Cisplatin, an effective antineoplastic agent, damages normal cells in a manner related to chemotherapy. Acetyl L-carnitine protects cells against mitochondrial and nuclear damage induced by chemotherapy.