The Protective Effects of Acetyl L-Carnitine on Testis Gonadotoxicity Induced by Cisplatin in Rats

Coskun, Neslihan; Hatipoglu, M.; ÖZOĞUL, CANDAN; Korkmaz, Cem; Akyol, Seda; CİLAKER MIÇILI, SERAP; Arik, Gulistan; ERDOĞAN, DENİZ

doi:10.5152/balkanmedj.2013.7340

The Protective Effects of Acetyl L-Carnitine on Testis Gonadotoxicity Induced by Cisplatin in Rats

Coskun N., Hatipoglu M. T., ÖZOĞUL C., Korkmaz C., Akyol S. N., CİLAKER MIÇILI S., ...More

BALKAN MEDICAL JOURNAL, vol.30, no.2, pp.235-241, 2013 (SCI-Expanded, Scopus, TRDizin)

Publication Type: Article / Article
Volume: 30 Issue: 2
Publication Date: 2013
Doi Number: 10.5152/balkanmedj.2013.7340
Journal Name: BALKAN MEDICAL JOURNAL
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Page Numbers: pp.235-241
Keywords: Acetyl L-carnitine, cisplatin, gonadotoxicity, testis
Dokuz Eylül University Affiliated: Yes

Abstract

Background: Cisplatin, an effective antineoplastic agent, damages normal cells in a manner related to chemotherapy. Acetyl L-carnitine protects cells against mitochondrial and nuclear damage induced by chemotherapy.