Serratia marcescens sepsis outbreak caused by contaminated propofol

ÇİLLİ F. F., NAZLI ZEKA A., ARDA B., SİPAHİ O. R., Aksit-Barik S., Kepeli N., ...More

AMERICAN JOURNAL OF INFECTION CONTROL, vol.47, no.5, pp.582-584, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 5
  • Publication Date: 2019
  • Doi Number: 10.1016/j.ajic.2018.10.014
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.582-584
  • Keywords: Propofol, Outbreak, Serratia marcescens, Extrinsic contamination, INFECTIONS, CARE
  • Dokuz Eylül University Affiliated: Yes


We presented a sepsis outbreak caused by Serratia marcescens from contaminated propofol to raise awareness. Three patients had sepsis syndrome after chest surgery. Isolation of S marcescens from patients' respiratory and blood samples alerted us to a possible outbreak. Four syringes filled with propofol and 1 saline solution yielded S marcescens. Nine of 10 isolates from samples of patients and environment genotyped by pulsed-field gel electrophoresis were the same. Disobeying aseptic injection rules of propofol is still causing outbreaks. (C) 2018 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.