Intestinal damage in gastroschisis correlates with the concentration of intraamniotic meconium

Api A., OLGUNER M., HAKGÜDER F. G., Ates O., Ozer E., Akgur F.

JOURNAL OF PEDIATRIC SURGERY, vol.36, no.12, pp.1811-1815, 2001 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 12
  • Publication Date: 2001
  • Doi Number: 10.1053/jpsu.2001.28846
  • Journal Name: JOURNAL OF PEDIATRIC SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1811-1815
  • Keywords: gastroschisis, intestinal damage, intraamniotic meconium, ALLANTOIC FLUID EXCHANGE, HUMAN NEONATAL URINE, AMNIOTIC-FLUID, TRANSABDOMINAL AMNIOINFUSION, SEVERE OLIGOHYDRAMNIOS, BOWEL, PREVENTION, ETIOLOGY, MODEL, DEFECATION
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background/Purpose: Contact with amniotic fluid (AF) causes intestinal damage in gastroschisis, which has been shown to be caused by intraamniotic meconium. However, whether this intraamniotic meconium-induced intestinal damage is concentration dependent has not been investigated previously. The purpose of this study is to investigate the effects of intraamniotic human meconium at various concentrations on the intestines of chick embryo with gastroschisis.