Tissue sodium stores in peritoneal dialysis patients.

Tintara S., Alsouqi A., Değer S. M., Bian A., Stewart T., Titze J., ...Daha Fazla

American Society of Nephrology, Kidney Week 2018, California, Amerika Birleşik Devletleri, 23 Ekim 2018, cilt.29, ss.597, (Özet Bildiri)

  • Yayın Türü: Bildiri / Özet Bildiri
  • Cilt numarası: 29
  • Basıldığı Şehir: California
  • Basıldığı Ülke: Amerika Birleşik Devletleri
  • Sayfa Sayıları: ss.597
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

water retention, particularly in the skin and muscle. Using 23Na-magnetic

resonance imaging (MRI), elevated tissue Na+ content was found in hemodialysis patients.

Peritoneal dialysis (PD) patients generally have higher residual kidney function than HD

patients, yet the effectiveness of PD in tissue Na+ removal has not been evaluated.

Methods: We examined tissue Na+ levels in 10 PD patients. PD patients were matched

with healthy controls by age, race, gender and body mass index (BMI). All study subjects

underwent 23Na-MRI to quantify Na+ levels in lower leg muscle and skin.

Results: We studied 10 PD patients and 41 controls. PD patients had significantly

higher skin and muscle Na+ levels compared to controls (figure 1). In PD subjects, skin Na+

level was inversely correlated to ultrafiltration volume, a marker of Na+ removal adequacy

(figure 2).

Conclusions: Our data suggest that PD patients have elevated tissue Na+ stores. The

mechanisms by which this abnormality develops and its consequences should be further

examined.

Funding: Commercial Support - Baxter Healthcare Corporation