Investigation of dose-dependent effects of berberine against renal ischemia/reperfusion injury in experimental diabetic rats

Kumas M., Eşrefoğlu M., Karatas E., Duymac N., Kanbay S., Ergün İ. S., ...More

NEFROLOGIA, vol.39, no.4, pp.411-423, 2019 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 4
  • Publication Date: 2019
  • Doi Number: 10.1016/j.nefro.2018.10.006
  • Journal Name: NEFROLOGIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.411-423
  • Keywords: Renal ischemia/reperfusion injury, Berberine, Histopathology, Oxidative stress, Apoptosis, Inflammation, TOTAL ANTIOXIDANT CAPACITY, C-REACTIVE PROTEIN, ISCHEMIA-REPERFUSION, CEREBRAL-ISCHEMIA, ATPASE ACTIVITY, KIDNEY, FAILURE, PATHOPHYSIOLOGY, IMPROVES, ALPHA
  • Dokuz Eylül University Affiliated: Yes


Background: Ischemia-reperfusion injury causes various severe morphological and functional changes in diabetic patients. To date, numerous antidiabetic and antioxidant agents have been used for treatment of the disease-related changes.