Investigation of dose-dependent effects of berberine against renal ischemia/reperfusion injury in experimental diabetic rats

Kumas, MELTEM; Eşrefoğlu, Mukaddes; Karatas, Ersin; Duymac, Nurcihan; Kanbay, Songul; Ergün, İlyas; Uyuklu, Mehmet; Koçyiğit, Abdürrahim

doi:10.1016/j.nefro.2018.10.006

Investigation of dose-dependent effects of berberine against renal ischemia/reperfusion injury in experimental diabetic rats

Kumas M., Eşrefoğlu M., Karatas E., Duymac N., Kanbay S., Ergün İ. S., ...Daha Fazla

NEFROLOGIA, cilt.39, sa.4, ss.411-423, 2019 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 39 Sayı: 4
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.nefro.2018.10.006
Dergi Adı: NEFROLOGIA
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.411-423
Anahtar Kelimeler: Renal ischemia/reperfusion injury, Berberine, Histopathology, Oxidative stress, Apoptosis, Inflammation
Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Background: Ischemia-reperfusion injury causes various severe morphological and functional changes in diabetic patients. To date, numerous antidiabetic and antioxidant agents have been used for treatment of the disease-related changes.