Gradient and Patterned Protein Films Stabilized via Nanoimprint Lithography for Engineered Interactions with Cells

Wang L., Duncan B., Tang R., Lee Y., Creran B., ELÇİ Ş. G., ...Daha Fazla

ACS APPLIED MATERIALS & INTERFACES, cilt.9, sa.1, ss.42-46, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9 Sayı: 1
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1021/acsami.6b13815
  • Dergi Adı: ACS APPLIED MATERIALS & INTERFACES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.42-46
  • Anahtar Kelimeler: biomaterial, nanoimprint lithography, inkjet printing, cell patterning thin films
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Protein-based biomaterials provide versatile scaffolds for generating functional surfaces for biomedical applications. However, tailoring the functional and biological properties of protein films remains a challenge. Here, we describe a high-throughput method to designing stable, functional biomaterials by combining inkjet deposition of protein inks with a nano imprint lithography based methodology. The translation of the intrinsically charged proteins into functional materials properties was demonstrated through controlled cellular adhesion. This modular strategy offers a rapid method to produce customizable biomaterials.