The Levels of Soluble CD40 Ligand and C-Reactive Protein in Normal Weight, Overweight and Obese People
CLINICAL MEDICINE & RESEARCH, cilt.8, sa.2, ss.89-95, 2010 (ESCI, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 8 Sayı: 2
- Basım Tarihi: 2010
- Doi Numarası: 10.3121/cmr.2010.889
- Dergi Adı: CLINICAL MEDICINE & RESEARCH
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
- Sayfa Sayıları: ss.89-95
- Anahtar Kelimeler: Body mass index, CD40 ligand, C-reactive protein, Inflammation, Obesity
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Dokuz Eylül Üniversitesi Adresli: Evet
Özet
Objective: Obesity has been suggested as an independent risk factor for cardiovascular disease. Increasing evidence shows that engagement of soluble CD40 ligand (sCD40L) with its receptor plays a crucial role in the pathogenesis of atherosclerosis. The aim of the present study was to test whether obesity is associated with low-grade systemic inflammation as measured by serum high-sensitive C-reactive protein (hsCRP) and sCD40L concentration.