Myeloid Cell-associated Resistance to PD-1/PD-L1 Blockade in Urothelial Cancer Revealed Through Bulk and Single-cell RNA Sequencing

Wang L., Sfakianos J. P., Beaumont K. G., Akturk G., Horowitz A., Sebra R. P., ...Daha Fazla

CLINICAL CANCER RESEARCH, cilt.27, sa.15, ss.4287-4300, 2021 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 15
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1158/1078-0432.ccr-20-4574
  • Dergi Adı: CLINICAL CANCER RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, BIOSIS, Biotechnology Research Abstracts, EMBASE, Gender Studies Database, MEDLINE
  • Sayfa Sayıları: ss.4287-4300
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Purpose To define dominant molecular and cellular features associated with PD-1/PD-L1 blockade resistance in metastatic urothelial cancer.