Myeloid Cell-associated Resistance to PD-1/PD-L1 Blockade in Urothelial Cancer Revealed Through Bulk and Single-cell RNA Sequencing

Wang L., Sfakianos J. P., Beaumont K. G., Akturk G., Horowitz A., Sebra R. P., ...More

CLINICAL CANCER RESEARCH, vol.27, no.15, pp.4287-4300, 2021 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 27 Issue: 15
  • Publication Date: 2021
  • Doi Number: 10.1158/1078-0432.ccr-20-4574
  • Journal Name: CLINICAL CANCER RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, BIOSIS, Biotechnology Research Abstracts, EMBASE, Gender Studies Database, MEDLINE
  • Page Numbers: pp.4287-4300
  • Dokuz Eylül University Affiliated: Yes

Abstract

Purpose To define dominant molecular and cellular features associated with PD-1/PD-L1 blockade resistance in metastatic urothelial cancer.