Definitive radiotherapy for 114 cases of T3N0 glottic carcinoma: influence of dose-volume parameters on outcome

Wylie J., Sen M., Swindell R., Sykes A., Farrington W., Slevin N.

RADIOTHERAPY AND ONCOLOGY, cilt.53, sa.1, ss.15-21, 1999 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 53 Sayı: 1
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1016/s0167-8140(99)00131-0
  • Dergi Adı: RADIOTHERAPY AND ONCOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.15-21
  • Anahtar Kelimeler: radiotherapy, glottic, local control, regional control, volume, dose
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Background and purpose: Assuming that the dose-response curve for T3N0M0 glottic carcinoma is steep and that the rate of occult lymph node metastases is low, it should be possible to employ high biological tumour doses to modest target volumes and thereby maximise laryngeal control without compromising final neck control. Within the constraints of a retrospective study we aim to examine this policy with respect to local control, incidence of nodal relapse and late complications.