Atıf İçin Kopyala
Isik S., Karaman M., Micili S., Caglayan-Sozmen S., BAĞRIYANIK H. A., Arikan-Ayyildiz Z., ...Daha Fazla
Allergologia et immunopathologia, cilt.46, sa.1, ss.67-75, 2018 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
46
Sayı:
1
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Basım Tarihi:
2018
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Doi Numarası:
10.1016/j.aller.2017.05.004
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Dergi Adı:
Allergologia et immunopathologia
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.67-75
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Anahtar Kelimeler:
Asthma, Airway remodelling, Angiogenesis, Apoptosis, Murine model, Sinomenine, Th2, MATRIX METALLOPROTEINASES, IN-VITRO, ACUTUM, PROLIFERATION, RATS, PHARMACOLOGY, INVOLVEMENT, EXPRESSION, DISEASES, INJURY
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Dokuz Eylül Üniversitesi Adresli:
Evet
Özet
Background: Sinomenine (SIN), an alkaloid isolated from the root of Sinomenium acutum which has a variety of pharmacological effects, including anti-inflammation, immunosuppression and anti-angiogenesis. The present study aimed to evaluate the effects of SIN on airway remodelling, epithelial apoptosis, and T Helper (Th)-2 derived cytokine levels in a murine model of chronic asthma.