Effect of hormonal changes on the neurological status in the menstrual cycle of patient with multiple sclerosis

Yorgun Y. G., ÖZAKBAŞ S.

CLINICAL NEUROLOGY AND NEUROSURGERY, cilt.186, 2019 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 186
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.clineuro.2019.105499
  • Dergi Adı: CLINICAL NEUROLOGY AND NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Multiple sclerosis, Menstrual cycle, Premenstrual worsening, Disability
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objectives: Premenstrual worsening has been often complained by patients with multiple sclerosis (MS). However, there is no quantitative study in the literature regarding premenstrual worsening and there are only a few studies for its reasons. In diseases such as MS, which there are limited evidence about the etiology and the triggers, detection of the variables in menstrual period, which is defined relatively easy, has a great potential to shed light to the disease. In the present study, we aimed to detect whether there was a deterioration in premenstrual period of patients with MS and to measure the observed deterioration and the relationships between demographics, physical and hormonal variables.