Can the Cell-free DNA Test Predict Placenta Accreta Spectrum or Placenta Previa Totalis?

Adiyaman D., Kuyucu M., Atakul B. K., Can D., Ozeren M., Koc A., ...More

ZEITSCHRIFT FUR GEBURTSHILFE UND NEONATOLOGIE, vol.226, no.02, pp.92-97, 2022 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 226 Issue: 02
  • Publication Date: 2022
  • Doi Number: 10.1055/a-1579-1338
  • Journal Name: ZEITSCHRIFT FUR GEBURTSHILFE UND NEONATOLOGIE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE
  • Page Numbers: pp.92-97
  • Keywords: cell-free DNA test, fetal fraction, placenta accreta spectrum, placenta previa, FREE FETAL DNA, MATERNAL PLASMA, PREGNANCIES, FRACTION, HEALTH
  • Dokuz Eylül University Affiliated: No

Abstract

Background Following the discovery that fetal DNA originates from the trophoblastic cells of the placenta, the contribution of the cell-free DNA test in placenta-related obstetric complications has begun to be investigated. Compared to uncomplicated pregnancies, higher fetal fractions were detected in placenta accreta spectrum and placenta previa, which are among placenta-related obstetric complications. However, this data applies only to advanced gestational weeks.