An evaluation of the effect of ertapenem in rats with sepsis created by cecal ligation and puncture

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Serin B. G., Kose Ş., YILMAZ O., Yildirim M., Akbulut I., Senger S. S., ...More

ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY, vol.25, no.5, pp.427-432, 2019 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 25 Issue: 5
• Publication Date: 2019
• Doi Number: 10.5505/tjtes.2018.26050
• Journal Name: ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
• Page Numbers: pp.427-432
• Keywords: Ertapenem, rat, sepsis, ADHESION FORMATION, PREVENTION, LAVAGE, PATHOPHYSIOLOGY, PATHOGENESIS, ANTIBIOTICS, MARKER
• Dokuz Eylül University Affiliated: Yes

Abstract

BACKGROUND: Intra-abdominal adhesions are still a major problem which is expected to be reduced by the provision of bacterial decontamination. Various antibiotics have been used to prevent the formation of adhesion in the septic abdomen. This study aims to investigate the efficacy of ertapenem in sepsis of rats induced by cecal ligation and puncture.