Effect of 1 alpha-25-dihydroxyvitamin D-3 on intimal hyperplasia developing in vascular anastomoses: a rabbit model

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Yurekli I., Gokalp O., KİRAY M., Bademci M., Yetkin U., Ergunes K., ...More

ARCHIVES OF MEDICAL SCIENCE, vol.9, no.3, pp.404-408, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 9 Issue: 3
  • Publication Date: 2013
  • Doi Number: 10.5114/aoms.2012.30786
  • Journal Name: ARCHIVES OF MEDICAL SCIENCE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.404-408
  • Keywords: carotid artery, vitamin D, intimal hyperplasia, VITAMIN-D, INJURY, INHIBITION, CELLS
  • Dokuz Eylül University Affiliated: Yes

Abstract

Introduction: A common problem encountered in routine daily practice of cardiovascular surgery is migration of smooth muscle cells leading to intimal hyperplasia developing at vascular anastomosis sites which then causes luminal narrowing. The aim of this study was to investigate the antiproliferative effect of 1,25 (OH)(2)D-3 on intimal hyperplasia.