Akademik Veri Yönetim Sistemi
Retina-Vitreus, cilt.17, sa.2, ss.136-140, 2009 (Scopus)
Medical records of two patients treated for radiation retinopathy in our clinic were evaluated retrospectively to assess the efficacy of various intravitreal injections. Age of the patients was 28 and 53. The time interval between radiotherapy and radiation retinopathy was 3 years in the first patient and one year in the second. First patient received no prior treatment. Second patient had a history of left vitrectomy for a presumed diagnosis of retinal vein occlusion at another institute. First patient's visual acuity was 2/10 in the right eye and 4/10 in the left eye while second petient's visual acuity was counting fingers at 2 meters in the right eye and counting fingers at 4 meters in the left eye. Their posterior segment examinations revealed changes compatible with radiation retinopathy. There was no retinal or disc neovascularization. Second patient had also signs of optic neuropathy in the left eye. Both patients had multiple intravitreal injections of triamcinolone acetonide, bevacizumab and pegaptanib sodium. Early after injections visual acuity and clinic manifestations became slightly better but re-injections deemed necessary due to recurrent macular oedema. There is no consensus on treatment of radiation retinopathy but intravitreal injections may limit the damage and have a role in the treatment of macular oedema due to radiation retinopathy.