Evaluation of Trabecular Bone Structure in Healthy and Diabetic Patients with Stage III/IV Periodontitis Using Fractal Analysis Method

Evaluation of Trabecular Bone Structure in Healthy and Diabetic Patients with Stage III/IV Periodontitis Using Fractal Analysis Method

İ.M. Güler1, A. Dikilitaş1, A. Muhterem1, E. Koyuncu2, A. Akcali1,3,4, M.E. Arayıcı5
1Dokuz Eylul University, Faculty of Dentistry, Department of Periodontology, Izmir, Turkey, 2Dokuz Eylul University, Faculty of Dentistry, Department of Clinical Sciences, Division of Oral, Dental and Maxillofacial Radiology, Izmir, Turkey, 3Dokuz Eylul University, Institute of Health Sciences, Department of Dental Biomaterials, Izmir, Turkey, 4Queen Mary University of London, Barts and The London School of Medicine & Dentistry, Institute of Dentistry, Centre for Oral Clinical Research, London, United Kingdom, 5Dokuz Eylul University, Faculty of Medicine, Department of Basic Medical Sciences, Division of Biostatics and Medical Informatics, Izmir, Turkey
Presentation Type
Preferred presentation type: Oral presentation

General data
Topic: A9: Periodontal diseases and systemic diseases

Abstract text
Background & Aim: To compare differences in trabecular microarchitecture in mandibular first molar interdental bone on panoramic radiographs using fractal analysis in stage III/IV periodontitis patients with and without diabetes mellitus (DM).
Methods: Clinical records (CAL, PD, BOP, PI, FI) and radiographic parameters (bone loss and density) were obtained from 12 systemically healthy (control) stage III/IV periodontitis patients and 12 individuals with stage III/IV periodontitis and DM at University setting. One region of interest (ROIs) was chosen bilaterally from the interdental bone around the mandibular first molar. The mean fractal dimension (FD) values of the ROIs were calculated.
Results: A total of 25 generalized periodontitis patients, including 12 with DM (4 patients: Stage III Grade B and 8 patients: Stage IV Grade C) and 13 controls (4 patients: Stage III Grade B and 9 patients: Stage IV Grade C) were included to the study. The mean age of the study population was 52.8 ± 1.3 and 62% (n = 17) were female. No significant difference was observed between patients with DM and the control group in terms of mandibular molar interdental FD values (1.58 ± 0.10 vs 1.55 ± 0.12, p = 0.243).
Conclusions: The presence of diabetes mellitus was not associated with reduced bone structure, as evaluated by fractal analysis in patients with similar periodontal conditions. Further investigation is required to assess different HbA1c levels grade modifier-in periodontitis patients with diabetes mellitus.