Role of Fanconi anemia/BRCA pathway genes in hepatocellular carcinoma chemoresistance
HEPATOLOGY RESEARCH, vol.46, no.12, pp.1264-1274, 2016 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 46 Issue: 12
- Publication Date: 2016
- Doi Number: 10.1111/hepr.12675
- Journal Name: HEPATOLOGY RESEARCH
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.1264-1274
- Keywords: BRCA1, chemosensitization, DSB DNA repair, Fanconi anemia, hepatocellular cancer, interstrand cross-linker drugs
- Dokuz Eylül University Affiliated: Yes
Abstract
Aim: To investigate the expression of DNA repair genes and the impact of the breast cancer 1, early onset (BRCA1) protein on chemoresistance of hepatocellular carcinoma (HCC).