Sleep Structure in Children With Attention-Deficit/Hyperactivity Disorder


Akinci G., ÖZTURA İ., HIZ A. S., Akdogan O., Karaarslan D., Ozek H., ...More

JOURNAL OF CHILD NEUROLOGY, vol.30, no.11, pp.1520-1525, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 11
  • Publication Date: 2015
  • Doi Number: 10.1177/0883073815573318
  • Journal Name: JOURNAL OF CHILD NEUROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1520-1525
  • Keywords: attention-deficit, hyperactivity disorder, children, sleep, nocturnal polysomnography, cyclic alternating pattern scoring, DEFICIT HYPERACTIVITY DISORDER, RESTLESS-LEGS-SYNDROME, CYCLIC ALTERNATING PATTERN, PLACEBO-CONTROLLED TRIAL, LIMB MOVEMENT-DISORDER, ONSET INSOMNIA, SYMPTOMS, DISTURBANCES, INSTABILITY, STANDARDS
  • Dokuz Eylül University Affiliated: Yes

Abstract

The authors evaluated basic sleep architecture and non-rapid eye movement (NREM) sleep alterations in drug-naive attention-deficit/hyperactivity disorder (ADHD) children without psychiatric or other comorbidities. This cross-sectional case-control study included 28 drug-naive children with ADHD and 15 healthy controls. This subjective studies revealed that children with ADHD had a worse sleep quality and increased daytime sleepiness. Polysomnography data showed that the sleep macrostructure was not significantly different in children with ADHD. Sleep microstructure was altered in ADHD children by means of reduced total cyclic alternating pattern rate and duration of cyclic alternating pattern sequences. This reduction was associated with a selective decrease of A1 index during stage 2 NREM. SpO2 in total sleep was slightly decreased; however, the incidence of sleep disordered breathing showed no significant difference. The authors suggest that cyclic alternating pattern scoring would provide a further insight to obtain a better understanding of the sleep structure in children with ADHD.