Invasive pneumococcal disease: From a tertiary care hospital in the post-vaccine era
Human Vaccines and Immunotherapeutics, cilt.13, sa.4, ss.962-964, 2017 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 13 Sayı: 4
- Basım Tarihi: 2017
- Doi Numarası: 10.1080/21645515.2016.1256519
- Dergi Adı: Human Vaccines and Immunotherapeutics
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.962-964
- Anahtar Kelimeler: antibiotic resistance, breakthrough infection, invasive pneumococcus disease, surveillance, Streptococcus pneumoniae, vaccination, vaccine failure
- Dokuz Eylül Üniversitesi Adresli: Hayır
Özet
A breakthrough infection occurring with 13-valent pneumococcal conjugate vaccine (PCV13) in Turkey are previously described. A breakthrough infection is defined as IPD in a child who had received ≥ 1 PCV-7 or PCV-13 and for which the pneumococcal isolate was a vaccine serotype. During one year period, among 6 patients with invasive pneumococcal infection, 2 patients were considered to have a vaccine failure with serotype 19F. Antibiotic resistance results were remarkable; macrolide resistance were observed in all strains except one, and high and intermediate penicillin resistance were determined in 2 strains.