The Role of Serum Bilirubin Levels in Predicting Troponin Positivity in Non-ST-Segment Elevation Acute Coronary Syndrome

Ozturk M., Askin L., Ipek E., Demirelli S., TURAN O. E., Yildirim E., ...More

ANGIOLOGY, vol.68, no.5, pp.414-418, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 68 Issue: 5
  • Publication Date: 2017
  • Doi Number: 10.1177/0003319716659583
  • Journal Name: ANGIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.414-418
  • Keywords: bilirubin, non-segment ST elevation acute coronary syndrome, troponin, ACUTE MYOCARDIAL-INFARCTION, LOW-DENSITY-LIPOPROTEIN, HEME OXYGENASE, ARTERY-DISEASE, OXIDATIVE STRESS, LYMPHOCYTE RATIO, ATHEROSCLEROSIS, SEVERITY, ASSOCIATION, ANTIOXIDANT
  • Dokuz Eylül University Affiliated: No

Abstract

Data are scant regarding serum bilirubin levels in non-ST-segment elevation acute coronary syndrome (NSTE-ACS). In this study, we evaluated the role of serum bilirubin levels in NSTE-ACS. We enrolled 782 patients who presented to the emergency department with acute chest pain. Patients were divided into 2 groups based on the troponin positivity. Patients with NSTE-ACS who had troponin positivity were included in group 1 (n = 382), and group 2 consisted of the control patients (n = 400). Direct bilirubin (DB) levels (group 1: 0.31 +/- 0.37 mg/dL, group 2: 0.20 +/- 0.25 mg/dL, P < .001) and total bilirubin (TB) levels (group 1: 0.78 +/- 0.56 mg/dL, group 2: 0.62 +/- 0.45 mg/dL, P < .001) were significantly higher in group 1. There was a significant and moderate correlation between serum bilirubin levels and admission troponin values (r = .34, P < .001 for TB and r = .42, P < .001 for DB). These results show that serum bilirubin levels were associated with troponin positivity in patients with NSTE-ACS.