Erythropoietin diminishes isoflurane-induced apoptosis in rat frontal cortex.

Creative Commons License

Öçmen E., Derbent A., Micilli S., Sönmez Ü., Aksu İ., Dayı A., ...More

Paediatric anaesthesia, vol.26, no.4, pp.444-51, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 4
  • Publication Date: 2016
  • Doi Number: 10.1111/pan.12867
  • Journal Name: Paediatric anaesthesia
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.444-51
  • Keywords: erythropoietin, rats, isoflurane, apoptosis, learning, memory, DEVELOPING BRAIN, NEUROCOGNITIVE FUNCTION, LEARNING-DEFICITS, NEUROTOXICITY, EXPOSURE, INJURY, DAMAGE, NEURODEGENERATION, ANESTHETICS, RECEPTOR
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background During the brain growth spurt, anesthetic drugs can cause cellular and behavioral changes in the developing brain. The aim of this study was to determine the neuroprotective effect of erythropoietin after isoflurane anesthesia in rat pups.