The Western Anatolia and the Aegean Sea regions are one of the most significant seismically active and rapidly deforming fields in the world. Generally, seismic activities cause deformations and these deformations are monitored with Global Positioning System (GPS) /Global Navigation System (GNSS). In this context, GPS data were used to determine the deformation of Izmir and its surrounding to estimate the relative plate motions. In this study, the kinematic structures of the faults, which control the seismic hazard in Izmir and its surroundings, processing results of the three-year (2009, 2010 and 2011) episodic GPS observations and the estimation of displacements for 21 GPS stations were presented. The aim of this study is to examine interplate motion of the stations and their relations with the tectonic structures, seismicity and paleomagnetism and additionally, to interprete the motions of the study area relative to different block motions. Consequently, the mean motion of the study area was found approximately 25 mm/yr (towards the SSW) in the Eurasia fixed frame solution. The Aegean block fixed frame and the Anatolian block fixed frame solutions were computed relative to Euler vectors. In Aegean and Anatolian block solutions it was determined that the stations move separately, not as a group. In Euler pole solution, some stations are separated from each other and meanwhile some stations are grouped by considering the differences and similarities of the station motions. According to this solution three lines and two regions were described in the study area. The relations between seismicity and paleomagnetic studies and the kinematic structures determined in Anatolian block fixed frame and Euler pole solution were also investigated. When the Anatolian block fixed frame solution and the earthquakes occurred between the years 1973 and 2011 were evaluated together, it was found that in the high seismically active region especially near to Sigacik bay, the motions of GPS stations were different even though their locations were close to each other. As a result of this, the relationship between the vector directions and active tectonism was determined. Additionally, in the Euler pole solution directions of the motion were found to be coherent with the paleomagnetic results, particularly in Urla and its surroundings. Here, the block fixed frame and Euler pole solutions and additionally, relations of them with seismicity and tectonism were mentioned as difference from previous studies. Besides, in this study, high importance was given to locate each station in main geological formations of the study area. (C) 2016 Elsevier Ltd. All rights reserved.