Coexistence of movement disorders and epilepsia partialis continua as the initial signs in probable Creutzfeldt-Jakob disease


Donmez B., Cakmur R., Men S., Oztura İ., Kitis A.

MOVEMENT DISORDERS, cilt.20, sa.9, ss.1220-1223, 2005 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 9
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1002/mds.20502
  • Dergi Adı: MOVEMENT DISORDERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1220-1223
  • Anahtar Kelimeler: chorea, Creutzfeldt-Jakob disease, epilepsia partialis continua
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Movement disorders and epilepsy rarely occur in the early stage of Creutzfeldt-Jakob disease (CJD) but have not been reported concurrently. We report on a 47-year-old patient with probable CJD who presented with generalized chorea and focal dystonia with myoclonic jerks on the right hand. Myoclonic jerks progressed to epilepsia partialis continua within 5 days of admission to the hospital. The diagnosis of our patient was compatible with probable CJD on the basis of clinical course, electroencephalogram, and diffusion-weighted magnetic resonance imaging findings, and presence of 14-3-3 protein in cerebrospinal fluid. To our knowledge, this is the first report of a case developing both movement disorders and epilepsia partialis continua in the early stage of the disease. (C) 2005 Movement Disorder Society.