Coexistence of movement disorders and epilepsia partialis continua as the initial signs in probable Creutzfeldt-Jakob disease
MOVEMENT DISORDERS, vol.20, no.9, pp.1220-1223, 2005 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 20 Issue: 9
- Publication Date: 2005
- Doi Number: 10.1002/mds.20502
- Journal Name: MOVEMENT DISORDERS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.1220-1223
- Keywords: chorea, Creutzfeldt-Jakob disease, epilepsia partialis continua
- Dokuz Eylül University Affiliated: Yes
Abstract
Movement disorders and epilepsy rarely occur in the early stage of Creutzfeldt-Jakob disease (CJD) but have not been reported concurrently. We report on a 47-year-old patient with probable CJD who presented with generalized chorea and focal dystonia with myoclonic jerks on the right hand. Myoclonic jerks progressed to epilepsia partialis continua within 5 days of admission to the hospital. The diagnosis of our patient was compatible with probable CJD on the basis of clinical course, electroencephalogram, and diffusion-weighted magnetic resonance imaging findings, and presence of 14-3-3 protein in cerebrospinal fluid. To our knowledge, this is the first report of a case developing both movement disorders and epilepsia partialis continua in the early stage of the disease. (C) 2005 Movement Disorder Society.