Coexistence of movement disorders and epilepsia partialis continua as the initial signs in probable Creutzfeldt-Jakob disease

Donmez B., Cakmur R., Men S., Oztura I., Kitis A.

MOVEMENT DISORDERS, no.9, pp.1220-1223, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Publication Date: 2005
  • Doi Number: 10.1002/mds.20502
  • Journal Name: MOVEMENT DISORDERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1220-1223
  • Keywords: chorea, Creutzfeldt-Jakob disease, epilepsia partialis continua, ABNORMALITIES, FEATURES
  • Dokuz Eylül University Affiliated: Yes

Abstract

Movement disorders and epilepsy rarely occur in the early stage of Creutzfeldt-Jakob disease (CJD) but have not been reported concurrently. We report on a 47-year-old patient with probable CJD who presented with generalized chorea and focal dystonia with myoclonic jerks on the right hand. Myoclonic jerks progressed to epilepsia partialis continua within 5 days of admission to the hospital. The diagnosis of our patient was compatible with probable CJD on the basis of clinical course, electroencephalogram, and diffusion-weighted magnetic resonance imaging findings, and presence of 14-3-3 protein in cerebrospinal fluid. To our knowledge, this is the first report of a case developing both movement disorders and epilepsia partialis continua in the early stage of the disease. (C) 2005 Movement Disorder Society.