Examination of adhesion molecules, homocysteine and hs-CRP in patients with polygenic hypercholesterolemia and isolated hypertriglyceridemia.

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Calan M., Calan Ö., GÖNEN M. S., Bilgir F., KEBAPCILAR L., Kulac E., ...More

Internal medicine (Tokyo, Japan), vol.50, no.15, pp.1529-35, 2011 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 15
  • Publication Date: 2011
  • Doi Number: 10.2169/internalmedicine.50.4297
  • Journal Name: Internal medicine (Tokyo, Japan)
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1529-35
  • Keywords: polygenic hypercholesterolemia, isolated hypertriglyceridemia, adhesion molecules, selectins, homocysteine, hs-CRP
  • Open Archive Collection: AVESIS Open Access Collection
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background Increased levels of selectins, adhesion molecules, hs-CRP and homocysteine are considered important as indicators of atherosclerosis. There is a significant amount of evidence that high LDL-C levels are a risk factor for coronary artery disease, whereas the relevance of isolated triglycerides is controversial. The present study aims to compare the levels of homocysteine, hs-CRP, E-selectin, sP-selectin, VCAM-1, ICAM-1 in patients with isolated hypertriglyceridemia and polygenic hypercholesterolemia.