Examination of adhesion molecules, homocysteine and hs-CRP in patients with polygenic hypercholesterolemia and isolated hypertriglyceridemia.

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Calan M., Calan Ö., GÖNEN M. S., Bilgir F., KEBAPCILAR L., Kulac E., ...Daha Fazla

Internal medicine (Tokyo, Japan), cilt.50, sa.15, ss.1529-35, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 50 Sayı: 15
  • Basım Tarihi: 2011
  • Doi Numarası: 10.2169/internalmedicine.50.4297
  • Dergi Adı: Internal medicine (Tokyo, Japan)
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1529-35
  • Anahtar Kelimeler: polygenic hypercholesterolemia, isolated hypertriglyceridemia, adhesion molecules, selectins, homocysteine, hs-CRP, LOW-DENSITY-LIPOPROTEIN, HEART-DISEASE, E-SELECTIN, CHOLESTEROL, VCAM-1, ATHEROSCLEROSIS, ASSOCIATION, EXPRESSION, ICAM-1, INTERLEUKIN-6
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background Increased levels of selectins, adhesion molecules, hs-CRP and homocysteine are considered important as indicators of atherosclerosis. There is a significant amount of evidence that high LDL-C levels are a risk factor for coronary artery disease, whereas the relevance of isolated triglycerides is controversial. The present study aims to compare the levels of homocysteine, hs-CRP, E-selectin, sP-selectin, VCAM-1, ICAM-1 in patients with isolated hypertriglyceridemia and polygenic hypercholesterolemia.