Effect of dexmedetomidine on acute lung injury in experimental ischemia-reperfusion model

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Kucukebe O. B., Ozzeybek D., Abdullayev R., Ustaoglu A., Tekmen I., KÜME T.

REVISTA BRASILEIRA DE ANESTESIOLOGIA, vol.67, no.2, pp.139-146, 2017 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 67 Issue: 2
• Publication Date: 2017
• Doi Number: 10.1016/j.bjan.2016.09.004
• Journal Name: REVISTA BRASILEIRA DE ANESTESIOLOGIA
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.139-146
• Keywords: Experimental, Dexmedetornidirie, Reperfusion injury, Acute lung injury, TUMOR-NECROSIS-FACTOR, LOWER-LIMB ISCHEMIA, ISCHEMIA/REPERFUSION, PATHOPHYSIOLOGY, PRETREATMENT, DYSFUNCTION, SURGERY, SHOCK
• Dokuz Eylül University Affiliated: Yes

Abstract

Purpose: Ischemia-reperfusion injury is one of the consequences of tourniquet application for extremity surgery. The aim of the study was to establish the effect of dexmedetomidine on the acute lung injury following lower extremity experimental ischemia-reperfusion model in rats.