The Role of Apelin 13 in Progression of Chronic Kidney Disease

Yavuz Y. C., SEVİNÇ C., Deniz M. S., Yavuz S., Altunoren O., Sayarlioglu H., ...More

IRANIAN JOURNAL OF KIDNEY DISEASES, vol.9, no.5, pp.369-373, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 9 Issue: 5
  • Publication Date: 2015
  • Journal Name: IRANIAN JOURNAL OF KIDNEY DISEASES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.369-373
  • Keywords: apelin 13, chronic kideney disease, glomerular filtration rate, BODY-MASS INDEX, RISK, DECLINE
  • Dokuz Eylül University Affiliated: No

Abstract

Introduction. Apelin is an adipokine secreted by the adipose tissue and by the endothelial cells in various parts of the body. Apelin is also expressed by the glomerular arteriolar rectus and glomerular capillary cells. We evaluated the relationship between the initial serum levels of apelin 13 with the trend of glomerular filtration rate (GFR) during a 1-year follow-up of patients with chronic kidney disease (CKD).