The effects of levosimendan and dobutamine in experimental bupivacaine-induced cardiotoxicity.
BMC anesthesiology, cilt.13, sa.1, ss.28, 2013 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 13 Sayı: 1
- Basım Tarihi: 2013
- Doi Numarası: 10.1186/1471-2253-13-28
- Dergi Adı: BMC anesthesiology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.28
- Anahtar Kelimeler: Bupivacaine, Cardiotoxicity, Levosimendan, Dobutamine, Rat
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Dokuz Eylül Üniversitesi Adresli: Evet
Özet
Background: Accidental intravenous exposure to bupivacaine is highly cardiotoxic and may lead to death. Positive inotropic agents are usually utilized in resuscitative efforts. We have compared the efficacy of levosimendan, a novel inotropic agent, with dobutamine and their combination in a rat model of bupivacaine intoxication.