Analysis of apoptotic, platelet-derived, endothelial-derived, and tissue factor-positive microparticles of children with acute lymphoblastic leukemia during induction therapy.

Yenigurbuz, Fatma; Kizmazoglu, DENİZ; Ateş, HALİL; Erdem, Melek; Tüfekçi, ÖZLEM; Yılmaz, ŞEBNEM; Ören, HALE

doi:10.1097/mbc.0000000000000811

Analysis of apoptotic, platelet-derived, endothelial-derived, and tissue factor-positive microparticles of children with acute lymphoblastic leukemia during induction therapy.

Yenigurbuz F. D., Kizmazoglu D., Ateş H., Erdem M., Tüfekçi Ö., Yılmaz Ş., ...Daha Fazla

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, cilt.30, sa.4, ss.149-155, 2019 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 30 Sayı: 4
Basım Tarihi: 2019
Doi Numarası: 10.1097/mbc.0000000000000811
Dergi Adı: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.149-155
Anahtar Kelimeler: acute lymphoblastic leukemia, childhood, microparticles, thromboembolism, CIRCULATING MICROPARTICLES, THROMBOSIS, CANCER, PREVALENCE, ACTIVATION, DISEASE, EVENTS, CELLS
Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objectives Thromboembolism is one of the most common complications during induction therapy of pediatric acute lymphoblastic leukemia (ALL). Procoagulant microparticles in the circulation may cause thromboembolic events. The aim of our study was to determine the levels of apoptotic, platelet-derived, endothelial-derived, and tissue factor-positive microparticles of children with ALL at diagnosis and during induction therapy.