Is There a Relationship Between Use of Anti-Vascular Endothelial Growth Factor Agents and Atrophic Changes in Age-Related Macular Degeneration Patients?

Kaynak S., KAYA M., KAYA D.

TURK OFTALMOLOJI DERGISI-TURKISH JOURNAL OF OPHTHALMOLOGY, cilt.48, sa.2, ss.81-84, 2018 (ESCI, Scopus, TRDizin) identifier identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 48 Sayı: 2
  • Basım Tarihi: 2018
  • Doi Numarası: 10.4274/tjo.27448
  • Dergi Adı: TURK OFTALMOLOJI DERGISI-TURKISH JOURNAL OF OPHTHALMOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.81-84
  • Anahtar Kelimeler: Anti-VEGF agents, geographic atrophy, age-related macular degeneration
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Choroidal neovascularization due to age-related macular degeneration (AMD) is currently treated successfully with anti-vascular endothelial growth factor (VEGF) intravitreal agents. Emerging evidence suggests that anti-VEGF treatment may potentially increase development of geographic atrophy. However, there is not yet direct proof of a causal relationship between geographic atrophy and use of anti-VEGF agents in nAMD. The aim of this review is to discuss the evidence concerning the association between anti-VEGF therapy and progression of geographic atrophy.