Cardiac Safety of Donepezil in Elderly Patients with Alzheimer Disease

IŞIK A. T., Yildiz G. B., Bozoglu E., Yay A., Aydemir E.

INTERNAL MEDICINE, cilt.51, sa.6, ss.575-578, 2012 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 51 Sayı: 6
  • Basım Tarihi: 2012
  • Doi Numarası: 10.2169/internalmedicine.51.6671
  • Dergi Adı: INTERNAL MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.575-578
  • Anahtar Kelimeler: Donepezil, cardiac safety, Alzheimer Disease, elderly, QT interval
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective Donepezil is a widely used cholinesterase inhibitor for the treatment of Alzheimer's disease (AD), however its cholinergic adverse side effects on the cardiovascular system are still unclear. In this study, we aimed to examine the adverse side effects caused by donepezil on cardiac rhythm and postural blood pressure changes in elderly patients with Alzheimer Disease.