Expression and activity levels of matrix metalloproteinase-7 and in situ localization of caseinolytic activity in colorectal cancer

Keles, Didem; Arslan, Baha; Terzi, Cem; Tekmen, Isil; Dursun, Ezgi; ALTUNGÖZ, OĞUZ; OKTAY, GÜLGÜN

doi:10.1016/j.clinbiochem.2014.06.004

Expression and activity levels of matrix metalloproteinase-7 and in situ localization of caseinolytic activity in colorectal cancer

Keles D., Arslan B., Terzi C., Tekmen I., Dursun E., ALTUNGÖZ O., ...Daha Fazla

CLINICAL BIOCHEMISTRY, cilt.47, ss.1265-1271, 2014 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 47
Basım Tarihi: 2014
Doi Numarası: 10.1016/j.clinbiochem.2014.06.004
Dergi Adı: CLINICAL BIOCHEMISTRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1265-1271
Anahtar Kelimeler: Matrix metalloproteinase-7, Casein zymography, In situ casein zymography, Colorectal cancer
Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objectives: Matrix metalloproteinase-7 is capable of degrading several ECM and non-ECM molecules and contributes to colorectal cancer progression and metastasis. Here, we examined the significance of MMP-7 in colorectal tumors by detecting active and latent MMP-7 levels and localization of its caseinolytic activity.