Insulin glargine compared with premixed insulin for management of insulin-naive type 2 diabetes patients uncontrolled on oral antidiabetic drugs: the open-label, randomized GALAPAGOS study

Aschner, Pablo; Sethi, Bipin; Gomez-Peralta, Fernando; Landgraf, Wolfgang; Loizeau, Virginie; Dain, Marie-Paule; Pilorget, Valerie; ÇÖMLEKÇİ, ABDURRAHMAN

doi:10.1016/j.jdiacomp.2015.04.003

Insulin glargine compared with premixed insulin for management of insulin-naive type 2 diabetes patients uncontrolled on oral antidiabetic drugs: the open-label, randomized GALAPAGOS study

Aschner P., Sethi B., Gomez-Peralta F., Landgraf W., Loizeau V., Dain M., ...More

JOURNAL OF DIABETES AND ITS COMPLICATIONS, vol.29, no.6, pp.838-845, 2015 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 29 Issue: 6
Publication Date: 2015
Doi Number: 10.1016/j.jdiacomp.2015.04.003
Journal Name: JOURNAL OF DIABETES AND ITS COMPLICATIONS
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.838-845
Keywords: GALAPAGOS, Hypoglycemia, Insulin glargine, Premixed insulin, Type 2 diabetes
Dokuz Eylül University Affiliated: Yes

Abstract

Aims: Demonstrate superiority of insulin glargine (+/- glulisine) strategy versus premixed insulin strategy for percentage of patients reaching HbA1c <7% (<53 mmol/mol) at study end without any documented symptomatic hypoglycemia (bloof glucose [BG] <= 3.1 mmol/L) in type 2 diabetes (T2DM) patients failing oral agents.