Construction of an Octahydropyrido[3,4-b]carbazole Skeleton

Oncuoglu S., Ergun Y., Hizliates C., Akyildiz V.

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, vol.57, no.8, pp.1330-1335, 2021 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 57 Issue: 8
  • Publication Date: 2021
  • Doi Number: 10.1134/s1070428021080133
  • Journal Name: RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Chemical Abstracts Core, Index Chemicus (IC)
  • Page Numbers: pp.1330-1335
  • Keywords: pyrido[3, 4-b]carbazole, pyrido[4, 3-b]carbazole, ellipticine, octahydropyrido-carbazole, ELLIPTICINE, POTENT, DNA
  • Dokuz Eylül University Affiliated: Yes

Abstract

The octahydropyridocarbazole skeleton is an important key structure for the synthesis of pyridocarbazole alkaloids, including the antineoplastic agent ellipticine and related compounds. In the present work, an octahydropyrido[3,4-b]carbazole derivative and a number of new tetrahydrocarbazole derivatives were synthesized utilizing a new synthetic pathway.