Involuntary movement in infants during vitamin B12 treatment

Tosun A., Aral Y. Z., Cecen E., Aydogdu A., Cakmak B. C.

TURKISH JOURNAL OF HEMATOLOGY, cilt.28, sa.4, ss.317-322, 2011 (SCI-Expanded, Scopus, TRDizin) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 4
  • Basım Tarihi: 2011
  • Doi Numarası: 10.5152/tjh.2011.18
  • Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.317-322
  • Anahtar Kelimeler: Involuntary movement, vitamin B12 deficiency, infant
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Megaloblastic anemia is rare in infants and is generally due to vitamin B12 (cobalamin) deficiency in the mother. Neurologic symptoms of vitamin B12 deficiency include irritability, failure to thrive, hypotonia, and developmental regression/delay. Herein we present 2 infants with vitamin B12 that developed movement disorder 5 d after initiation of vitamin B12 treatment. Symptoms included tremor and myoclonus, involving in particular the face, tongue, and hands. Clinical findings in infants associated with vitamin B12 deficiency vary, and temporary involuntary movement can be observed during vitamin B12 therapy. (Turk J Hematol 2011; 28: 317-22)