Acetylcholinesterase inhibition and insulin resistance in late onset Alzheimer's disease


IŞIK A. T., Bozoglu E.

INTERNATIONAL PSYCHOGERIATRICS, vol.21, no.6, pp.1127-1133, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 6
  • Publication Date: 2009
  • Doi Number: 10.1017/s1041610209990664
  • Journal Name: INTERNATIONAL PSYCHOGERIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Page Numbers: pp.1127-1133
  • Keywords: galantamine, Alzheimer's, insulin resistance, elderly, GLUCOSE-METABOLISM, COGNITIVE FUNCTION, DIABETES-MELLITUS, BUTYRYLCHOLINESTERASE, INFLAMMATION, GALANTAMINE, POPULATION, HYPOTHESIS, BRAIN, MODEL
  • Dokuz Eylül University Affiliated: No

Abstract

Background: Insulin resistance (IR) may play a role in most pathogenic processes that promote the development of late onset Alzheimer's disease (LOAD). This study was designed to evaluate whether galantamine influenced peripheral IR in LOAD.