Association of mechanical bowel preparation with oral antibiotics and anastomotic leak following left sided colorectal resection: an international, multi-centre, prospective audit

Glasbey J. C., Blanco-Colino R., Kelly M., Singh B., Nepogodiev D., Bhangu A., ...More

COLORECTAL DISEASE, vol.20, pp.15-32, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20
  • Publication Date: 2018
  • Doi Number: 10.1111/codi.14362
  • Journal Name: COLORECTAL DISEASE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.15-32
  • Keywords: Colorectal surgery, colonic cancer, laparoscopic surgery, bowel preparation, anastomotic leak, SURGICAL SITE INFECTION, GASTROINTESTINAL SURGERY, RANDOMIZED-TRIAL, COLON SURGERY, METAANALYSIS, COMPLICATIONS, PROPHYLAXIS, COLECTOMY, OUTCOMES, ILEUS
  • Dokuz Eylül University Affiliated: No

Abstract

IntroductionThe optimal bowel preparation strategy to minimise the risk of anastomotic leak is yet to be determined. This study aimed to determine whether oral antibiotics combined with mechanical bowel preparation (MBP+Abx) was associated with a reduced risk of anastomotic leak when compared to mechanical bowel preparation alone (MBP) or no bowel preparation (NBP).